| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | GCDH/GCD Positive Control for STJ507756 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | GCDH |
| Gene ID: | 2639 |
| Uniprot ID: | GCDH_HUMAN |
| Immunogen Region: | 200-250 |
| Specificity: | This is positive control is recommended for use in combination with GCDH/GCD antibody STJ507756. |
| Immunogen: | Synthetic peptide corresponding to amino acids within region 200-250 on Human GCDH/GCD protein protein. |
| Function | Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive. |
| Peptide Name | Glutaryl-Coa Dehydrogenase - MitochondrialGcd |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Peptide Names | Glutaryl-Coa Dehydrogenase - Mitochondrial proteinGcd proteinGCDH protein |
Information sourced from Uniprot.org