| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GAN Blocking Peptide for STJ507836 is synthetically produced from the 400-450 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
GAN |
| Gene ID: |
8139 |
| Uniprot ID: |
GAN_HUMAN |
| Immunogen Region: |
400-450 |
| Specificity: |
This blocking peptide is recommended for use in combination with GAN antibody, STJ507836 |
| Immunogen: |
Synthetic peptide corresponding to amino acids within region 400-450 on human DNA-binding protein SATB2 protein. |
| Post Translational Modifications | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. |
| Function | Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival. |
| Peptide Name | GigaxoninKelch-Like Protein 16 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Peptide Names | Gigaxonin proteinKelch-Like Protein 16 proteinGAN proteinGAN1 proteinKLHL16 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
