| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | GADD34 Blocking Peptide for STJ501133 is synthetically produced from the 380-400 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Immunogen Region: | 380-400 |
| Specificity: | This blocking peptide is recommended for use in combination with GADD34 antibody, STJ501133 |
| Immunogen: | Synthetic peptide corresponding to internal sequence of amino acids 380-400 of Human GADD34, covalently modified and coupled to a carrier protein. Sequence: PATGVFLKSWVYQPGEDTEEE |
| Background | Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1. This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. |
Information sourced from Uniprot.org
