| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | FGD3 Blocking Peptide for STJ501024 is synthetically produced from the 250-320 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | FGD3 |
| Gene ID: | 89846 |
| Uniprot ID: | FGD3_HUMAN |
| Immunogen Region: | 250-320 |
| Specificity: | This blocking peptide is recommended for use in combination with FGD3 antibody, STJ501024 |
| Immunogen: | Synthetic peptide taken within amino acid region 250-320 on human FYVE, RhoGEF and PH domain-containing protein 3. |
| Function | Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. |
| Peptide Name | Fyve - Rhogef And Ph Domain-Containing Protein 3Zinc Finger Fyve Domain-Containing Protein 5 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Peptide Names | Fyve - Rhogef And Ph Domain-Containing Protein 3 proteinZinc Finger Fyve Domain-Containing Protein 5 proteinFGD3 proteinZFYVE5 protein |
Information sourced from Uniprot.org