| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Estrogen Related Receptor gamma Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
ESRRG |
| Gene ID: |
2104 |
| Uniprot ID: |
ERR3_HUMAN |
| Immunogen: |
Estrogen-related receptor gamma/ERR3 |
| Post Translational Modifications | Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. |
| Function | Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle. |
| Peptide Name | Estrogen-Related Receptor GammaErr Gamma-2Estrogen Receptor-Related Protein 3Nuclear Receptor Subfamily 3 Group B Member 3 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Estrogen-Related Receptor Gamma proteinErr Gamma-2 proteinEstrogen Receptor-Related Protein 3 proteinNuclear Receptor Subfamily 3 Group B Member 3 proteinESRRG proteinERR3 proteinERRG2 proteinKIAA0832 proteinNR3B3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
