Estrogen Related Receptor gamma Blocking Peptide peptide (STJ505659)

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STJ505659-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Estrogen Related Receptor gamma Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ESRRG
Gene ID: 2104
Uniprot ID: ERR3_HUMAN
Immunogen: Estrogen-related receptor gamma/ERR3
Post Translational Modifications Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
Function Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle.
Peptide Name Estrogen-Related Receptor Gamma
Err Gamma-2
Estrogen Receptor-Related Protein 3
Nuclear Receptor Subfamily 3 Group B Member 3
Database Links Reactome: R-HSA-383280
Cellular Localisation Nucleus
Alternative Peptide Names Estrogen-Related Receptor Gamma protein
Err Gamma-2 protein
Estrogen Receptor-Related Protein 3 protein
Nuclear Receptor Subfamily 3 Group B Member 3 protein
ESRRG protein
ERR3 protein
ERRG2 protein
KIAA0832 protein
NR3B3 protein

Information sourced from Uniprot.org

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