| Short Description : | ergo-1 Positive Control for STJ500959 is synthetically produced from the 790-840 sequence and is suitable for use in western blot applications. |
| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | WB: 1:500 |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Immunogen: | Synthetic peptide taken within amino acid region 790-840 on C.elegans Endogenous-RNAi deficient arGOnaute protein. |
| Immunogen Region: | 790-840 |
| Specificity: | This is positive control is recommended for use in combination with ergo-1 antibody STJ500959. |
| Background | Argonaute protein required for gene silencing in the endogenous RNA interference (RNAi) pathway. Interacts with 26G small interfering RNAs (26G-siRNAs) and required for subsequent biogenesis of secondary 22G-siRNAs. May be involved in passenger strand cleavage of target 26G-siRNAs (PubMed: 22102828). |
Information sourced from Uniprot.org