| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | EPAC2 Blocking Peptide for STJ500902 is synthetically produced from the 743-762 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Rapgef4 |
| Uniprot ID: | RPGF4_RAT |
| Immunogen Region: | 743-762 |
| Specificity: | This blocking peptide is recommended for use in combination with EPAC2 antibody, STJ500902 |
| Immunogen: | Synthetic peptide corresponding to amino acids 743-762 of Epac2 protein. Sequence: CPREQFDSLTPLPEQEGPT |
| Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2. |
| Peptide Name | Rap Guanine Nucleotide Exchange Factor 4Exchange Factor Directly Activated By Camp 2Exchange Protein Directly Activated By Camp 2Epac 2Camp-Regulated Guanine Nucleotide Exchange Factor IiCamp-Gefii |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Peptide Names | Rap Guanine Nucleotide Exchange Factor 4 proteinExchange Factor Directly Activated By Camp 2 proteinExchange Protein Directly Activated By Camp 2 proteinEpac 2 proteinCamp-Regulated Guanine Nucleotide Exchange Factor Ii proteinCamp-Gefii proteinRapgef4 proteinCgef2 proteinEpac2 protein |
Information sourced from Uniprot.org