| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
EHD2 Positive Control for STJ500854 is synthetically produced from the 420-450 sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
EHD2 |
| Gene ID: |
30846 |
| Uniprot ID: |
EHD2_HUMAN |
| Immunogen Region: |
420-450 |
| Specificity: |
This is positive control is recommended for use in combination with EHD2 antibody STJ500854. |
| Immunogen: |
Synthetic peptide taken within amino acid 420-450 on human EH-Domain Containing Protein 2. |
| Tissue Specificity | Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle. |
| Function | ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane. |
| Peptide Name | Eh Domain-Containing Protein 2Past Homolog 2 |
| Database Links | Reactome: R-HSA-983231 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideMembraneCaveolaEndosome MembraneCytoplasmCytosolColocalizes With Glut4 In Intracellular Tubulovesicular Structures That Are Associated With Cortical F-ActinColocalizes With Fer1l5 At Plasma Membrane In Myoblasts And Myotubes |
| Alternative Peptide Names | Eh Domain-Containing Protein 2 proteinPast Homolog 2 proteinEHD2 proteinPAST2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
