| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | E2F5 Positive Control for STJ500830 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | E2f5 |
| Gene ID: | 13559 |
| Uniprot ID: | E2F5_MOUSE |
| Specificity: | This is positive control is recommended for use in combination with E2F5 antibody STJ500830. |
| Function | Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis. |
| Peptide Name | Transcription Factor E2f5E2f-5 |
| Database Links | Reactome: R-MMU-1538133Reactome: -MMU-2173796Reactome: -MMU-69231 |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Transcription Factor E2f5 proteinE2f-5 proteinE2f5 protein |
Information sourced from Uniprot.org