E2F4 Blocking Peptide for STJ500826 peptide (STJ503989)

SKU:
STJ503989-250
£281.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : E2F4 Blocking Peptide for STJ500826 is synthetically produced from the 360-410 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: E2f4
Gene ID: 104394
Uniprot ID: E2F4_MOUSE
Immunogen Region: 360-410
Specificity: This blocking peptide is recommended for use in combination with E2F4 antibody, STJ500826
Immunogen: Synthetic peptide taken within amino acid region 360-410 on mouse E2F4 protein.
Post Translational Modifications Differentially phosphorylated in vivo.
Function Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTCCGCGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Peptide Name Transcription Factor E2f4
E2f-4
Database Links Reactome: R-MMU-1538133
Reactome: -MMU-2173796
Reactome: -MMU-69231
Cellular Localisation Nucleus
Alternative Peptide Names Transcription Factor E2f4 protein
E2f-4 protein
E2f4 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ504031 E2F4 Positive Control for STJ500826 peptide (STJ504031) WB
STJ500826 Anti-E2F4 antibody (360-410) {Biotin} (STJ500826) Rabbit Polyclonal Mouse ELISA/IP/WB
STJ504998 Thickveins Peptide Blocking Peptide peptide (STJ504998) Immunodepletion/Immunocompetition
STJ505377 hCG beta Peptide Blocking Peptide peptide (STJ505377) Immunodepletion/Immunocompetition
STJ505378 hCG beta Peptide Blocking Peptide peptide (STJ505378) Immunodepletion/Immunocompetition

Related Products

!