Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Dnmt2 Positive Control for STJ506248 is synthetically produced from the 350-400 sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | Trdmt1 |
Gene ID: | 13434 |
Uniprot ID: | TRDMT_MOUSE |
Immunogen Region: | 350-400 |
Specificity: | This is positive control is recommended for use in combination with Dnmt2 antibody STJ506248. |
Tissue Specificity | Highly expressed in thymus, testis, and at much lower levels in spleen, lung, brain, heart, kidney, liver, skeletal muscle and embryonic stem cells. |
Function | Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). Has higher activity on tRNA(Asp) modified with queuosine at position 34. |
Peptide Name | TrnaCytosine(38-C(5-MethyltransferaseDnaCytosine-5-Methyltransferase-Like Protein 2Dnmt2Dna Methyltransferase Homolog MmuiipDna Mtase Homolog MmuiipM.mmuiipMet-2 |
Cellular Localisation | Cytoplasm |
Alternative Peptide Names | Trna proteinCytosine(38-C(5-Methyltransferase proteinDna proteinCytosine-5-Methyltransferase-Like Protein 2 proteinDnmt2 proteinDna Methyltransferase Homolog Mmuiip proteinDna Mtase Homolog Mmuiip proteinM.mmuiip proteinMet-2 proteinTrdmt1 proteinDnmt2 proteinMet2 protein |
Information sourced from Uniprot.org