Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
DEK Blocking Peptide is synthetically produced from the 300-330 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
DEK |
Gene ID: |
7913 |
Uniprot ID: |
DEK_HUMAN |
Immunogen Region: |
300-330 |
Immunogen: |
Synthetic peptide taken within amino acid region 300-330 on C terminal region of Human Draxin protein. Region: NNKCFDDCMC VEGLRCYAKF HRNRRVTRRK |
Tissue Specificity | Ubiquitous. Expressed at relatively high levels. |
Post Translational Modifications | Phosphorylated by CK2. Phosphorylation fluctuates during the cell cycle with a moderate peak during G(1) phase, and weakens the binding of DEK to DNA. |
Function | Involved in chromatin organization. |
Peptide Name | Protein Dek |
Database Links | Reactome: R-HSA-5250924Reactome: R-HSA-8864260Reactome: R-HSA-9616222 |
Cellular Localisation | NucleusEnriched In Regions Where Chromatin Is Decondensed Or Sparse In The Interphase Nuclei |
Alternative Peptide Names | Protein Dek proteinDEK protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance