| Short Description : | DEK Blocking Peptide is synthetically produced from the 300-330 sequence and is suitable for use in western blot applications. |
| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | DEK |
| Gene ID: | 7913 |
| Uniprot ID: | DEK_HUMAN |
| Immunogen: | Synthetic peptide taken within amino acid region 300-330 on C terminal region of Human Draxin protein. Region: NNKCFDDCMC VEGLRCYAKF HRNRRVTRRK |
| Immunogen Region: | 300-330 |
| Tissue Specificity | Ubiquitous. Expressed at relatively high levels. |
| Post Translational Modifications | Phosphorylated by CK2. Phosphorylation fluctuates during the cell cycle with a moderate peak during G(1) phase, and weakens the binding of DEK to DNA. |
| Function | Involved in chromatin organization. |
| Peptide Name | Protein Dek |
| Database Links | Reactome: R-HSA-5250924Reactome: R-HSA-8864260Reactome: R-HSA-9616222 |
| Cellular Localisation | NucleusEnriched In Regions Where Chromatin Is Decondensed Or Sparse In The Interphase Nuclei |
| Alternative Peptide Names | Protein Dek proteinDEK protein |
Information sourced from Uniprot.org