| Short Description : | Recombinant-Cynomolgus/Rhesus macaque TNFRSF9/4-1BB-C-His protein was developed in hek293 cells using the region Leu24-Gln186. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen: | Recombinant CynomolgusTNFRSF9/4-1BB Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Leu24-Gln186) of Cynomolgus TNFRSF9 fused with His tag at the C-terminus. |
| Immunogen Region: | Leu24-Gln186 |
| Immunogen Sequence: | LQDLCSNCPAGTFCDNNRSQ ICSPCPPNSFSSAGGQRTCD ICRQCKGVFKTRKECSSTSN AECDCISGYHCLGAECSMCE QDCKQGQELTKKGCKDCCFG TFNDQKRGICRPWTNCSLDG KSVLVNGTKERDVVCGPSPA DLSPGASSATPPAPAREPGH SPQ |
| Background | 4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. |
Information sourced from Uniprot.org
