| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen Region: | Pro94-Leu233 |
| Immunogen: | Recombinant Cynomolgus NKG2A&KLRD1/CD159a&CD94 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Pro94-Leu233) & (Lys32-Ile179) of Cynomolgus NKG2A&KLRD1/CD159a&CD94 (Accession #) fused with His tag |
| Background | The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies. |
Information sourced from Uniprot.org
