Cynomolgus IL-17F protein (Recombinant) (C-His) (STJP020269)

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STJP020269-100
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Unconjugated
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Immunogen Region: Arg31-Gln163
Immunogen: Recombinant Cynomolgus IL-17F Protein is expressed from Expi293 with His tag at the C-terminal.；It contains Arg31-Gln163.
Background The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F) , are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N?terminus.IL-17F is ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover.

Information sourced from Uniprot.org

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