| Short Description : | Recombinant-Cynomolgus FcRn/FCGRT&B2M-C-His&Avi protein was developed in hek293 cells using the region Met1-Ser297. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Biotin |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen: | Biotinylated Recombinant Cynomolgus FcRn/FCGRT&B2M Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Met1-Ser297 (FCGRT) &Met1-Met119 (B2M) ) of Cynomolgus FcRn fused with a His tag and Avi tag at the C- |
| Immunogen Region: | Met1-Ser297 |
| Background | The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14, and forms an MHC class I-like heterodimer. |
Information sourced from Uniprot.org
