| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen Region: | Glu19-Phe252 |
| Immunogen: | Recombinant Cynomolgus DNAM-1/CD226 Protein is expressed from Expi293 with His tag at the C-terminal.；It contains Glu19-Phe252. |
| Immunogen Sequence: | EEVLWHTSVPFAENMSLECV YPSVGILTQVEWFKIGTEKD SIAIFSPTHGMVIRKPYAER VYFLNSTMASNNMTLFFRNA SEDDVGYYSCSLYTYPQGTW QKVIQVVQSDGFEAAVPPNS HIVSEPGKNITLTCQPQMTW PVQEVRWEKVQPHQIDLLTY CDLVHGRNFTSKFPRQIVSN CSHGSWSFIVVPDVTASDSG LYRCHLQASAGENETFVMRL TVAEGQTDNQYTRF |
| Background | DNAX accessory molecule-1 (DNAM-1) , also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. |
Information sourced from Uniprot.org
