| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.22um filtered solution in PBS (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen: | Recombinant Cynomolgus CD3 epsilon/CD3E Protein is produced by mammalian expression system. The target protein is expressed with sequence (Gln22-Asp117) of cynomolgus Cynomolgus CD3 Epsilon (Accession #) fused with a His tag at the C-terminus. |
| Immunogen Region: | Gln22-Asp117 |
| Background | CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8+ naive T cells) and also T helper cells (CD4+ naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3 Gamma chain, a CD3 Delta chain, and two CD3 Epsilon chains. |
Information sourced from Uniprot.org
