| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | CXCR1 Blocking Peptide for STJ500645 is synthetically produced from the 272-350 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | CXCR1 |
| Gene ID: | 3577 |
| Uniprot ID: | CXCR1_HUMAN |
| Immunogen Region: | 272-350 |
| Specificity: | This blocking peptide is recommended for use in combination with CXCR1 antibody, STJ500645 |
| Immunogen: | Synthetic peptide, corresponding to a region within C terminal amino acids 272-350 of Human CXCR1. |
| Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. |
| Peptide Name | C-X-C Chemokine Receptor Type 1Cxc-R1Cxcr-1Cdw128aHigh Affinity Interleukin-8 Receptor AIl-8r AIl-8 Receptor Type 1Cd Antigen Cd181 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | C-X-C Chemokine Receptor Type 1 proteinCxc-R1 proteinCxcr-1 proteinCdw128a proteinHigh Affinity Interleukin-8 Receptor A proteinIl-8r A proteinIl-8 Receptor Type 1 proteinCd Antigen Cd181 proteinCXCR1 proteinCMKAR1 proteinIL8RA protein |
Information sourced from Uniprot.org