Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | CD2 Blocking Peptide for STJ500438 is synthetically produced from the 300-335 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | CD2 |
Gene ID: | 914 |
Uniprot ID: | CD2_HUMAN |
Immunogen Region: | 300-335 |
Specificity: | This blocking peptide is recommended for use in combination with CD2 antibody, STJ500438 |
Immunogen: | Synthetic peptide corresponding to amino acid region 300-335 on human T-cell surface antigen CD2 protein. |
Tissue Specificity | Expressed in natural killer cells (at protein level). |
Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
Peptide Name | T-Cell Surface Antigen Cd2 Erythrocyte Receptor Lfa-2 Lfa-3 Receptor Rosette Receptor T-Cell Surface Antigen T11/Leu-5 Cd Antigen Cd2 |
Database Links | Reactome: R-HSA-202733 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Peptide Names | T-Cell Surface Antigen Cd2 protein Erythrocyte Receptor protein Lfa-2 protein Lfa-3 Receptor protein Rosette Receptor protein T-Cell Surface Antigen T11/Leu-5 protein Cd Antigen Cd2 protein CD2 protein SRBC protein |
Information sourced from Uniprot.org