CD10 Blocking Peptide peptide (STJ504410)

SKU:
STJ504410-250

£289.50
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: CD10 Blocking Peptide is synthetically produced from the 360-410 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: MME
Gene ID: 4311
Uniprot ID: NEP_HUMAN
Immunogen Region: 360-410
Immunogen: Synthetic peptide taken within amino acid region 360-410 on human Neprilysin protein.
Post Translational Modifications Myristoylation is a determinant of membrane targeting. Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity.
Function Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Peptide Name Neprilysin
Atriopeptidase
Common Acute Lymphocytic Leukemia Antigen
Calla
Enkephalinase
Neutral Endopeptidase 24.11
Nep
Neutral Endopeptidase
Skin Fibroblast Elastase
Sfe
Cd Antigen Cd10
Database Links Reactome: R-HSA-2022377
Reactome: R-HSA-5578768
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Peptide Names Neprilysin protein
Atriopeptidase protein
Common Acute Lymphocytic Leukemia Antigen protein
Calla protein
Enkephalinase protein
Neutral Endopeptidase 24.11 protein
Nep protein
Neutral Endopeptidase protein
Skin Fibroblast Elastase protein
Sfe protein
Cd Antigen Cd10 protein
MME protein
EPN protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance