Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
CCR1 Blocking Peptide for STJ500396 is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
CCR1 |
Gene ID: |
1230 |
Uniprot ID: |
CCR1_HUMAN |
Immunogen Region: |
1-50 |
Specificity: |
This blocking peptide is recommended for use in combination with CCR1 antibody, STJ500396 |
Immunogen: |
Synthetic peptide taken within amino acid region 1-50 on mouse CCR1 protein. |
Tissue Specificity | Widely expressed in different hematopoietic cells. |
Function | Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. |
Peptide Name | C-C Chemokine Receptor Type 1C-C Ckr-1Cc-Ckr-1Ccr-1Ccr1Hm145Ld78 ReceptorMacrophage Inflammatory Protein 1-Alpha ReceptorMip-1alpha-RRantes-RCd Antigen Cd191 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Peptide Names | C-C Chemokine Receptor Type 1 proteinC-C Ckr-1 proteinCc-Ckr-1 proteinCcr-1 proteinCcr1 proteinHm145 proteinLd78 Receptor proteinMacrophage Inflammatory Protein 1-Alpha Receptor proteinMip-1alpha-R proteinRantes-R proteinCd Antigen Cd191 proteinCCR1 proteinCMKBR1 proteinCMKR1 proteinSCYAR1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance