C1orf187 Positive Control peptide (STJ503981)

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STJ503981-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : C1orf187 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500-1:1, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: DRAXIN
Gene ID: 374946
Uniprot ID: DRAXI_HUMAN
Function Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
Peptide Name Draxin
Dorsal Inhibitory Axon Guidance Protein
Dorsal Repulsive Axon Guidance Protein
Neucrin
Cellular Localisation Secreted
Alternative Peptide Names Draxin protein
Dorsal Inhibitory Axon Guidance Protein protein
Dorsal Repulsive Axon Guidance Protein protein
Neucrin protein
DRAXIN protein
C1orf187 protein
PSEC0258 protein
UNQ3119 protein
PRO10268 protein

Information sourced from Uniprot.org

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