| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | C1orf187 Blocking Peptide is synthetically produced from the 300-330 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | DRAXIN |
| Gene ID: | 374946 |
| Uniprot ID: | DRAXI_HUMAN |
| Immunogen Region: | 300-330 |
| Immunogen: | Synthetic peptide taken within amino acid region 300-330 on C terminal region of Human Draxin protein. Region: NNKCFDDCMC VEGLRCYAKF HRNRRVTRRK |
| Function | Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. |
| Peptide Name | DraxinDorsal Inhibitory Axon Guidance ProteinDorsal Repulsive Axon Guidance ProteinNeucrin |
| Cellular Localisation | Secreted |
| Alternative Peptide Names | Draxin proteinDorsal Inhibitory Axon Guidance Protein proteinDorsal Repulsive Axon Guidance Protein proteinNeucrin proteinDRAXIN proteinC1orf187 proteinPSEC0258 proteinUNQ3119 proteinPRO10268 protein |
Information sourced from Uniprot.org