| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Bestrophin 3 Blocking Peptide is synthetically produced from the C-Term sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | BEST3 |
| Gene ID: | 144453 |
| Uniprot ID: | BEST3_HUMAN |
| Immunogen Region: | C-Term |
| Immunogen: | Synthetic peptide taken within the last 50 amino acids from the C-terminus of human Bestrophin-3 protein. |
| Tissue Specificity | Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina. |
| Function | Ligand-gated anion channel that allows the movement of chloride monoatomic anions across cell membranes when activated by calcium (Ca2+). |
| Peptide Name | Bestrophin-3Vitelliform Macular Dystrophy 2-Like Protein 3 |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Bestrophin-3 proteinVitelliform Macular Dystrophy 2-Like Protein 3 proteinBEST3 proteinVMD2L3 protein |
Information sourced from Uniprot.org