| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Bestrophin 3 Blocking Peptide is synthetically produced from the C-Term sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Best3 |
| Gene ID: |
382427 |
| Uniprot ID: |
BEST3_MOUSE |
| Immunogen Region: |
C-Term |
| Immunogen: |
Synthetic peptide taken within the last 50 amino acids from the C-terminus of rat Bestrophin-3 protein. |
| Tissue Specificity | Isoform 1: Expressed in heart. Isoform 2: Expressed in brain, retina/retinal pigment epithelium (RPE) and skeletal muscle. Expressed in acinar cells of parotid glands. Expressed in lung, kidney and testis. |
| Function | Isoform 1: Ligand-gated anion channel that allows the movement of chloride monoatomic anions across cell membranes when activated by calcium (Ca2+). Isoform 2: Does not function as calcium-gated chloride channel. |
| Peptide Name | Bestrophin-3Vitelliform Macular Dystrophy 2-Like Protein 3 |
| Database Links | Reactome: R-MMU-2672351 |
| Cellular Localisation | Isoform 1: Cell MembraneLocalized Also In Punctate Structures In The Cytosolic CompartmentIsoform 2: Cell Membrane |
| Alternative Peptide Names | Bestrophin-3 proteinVitelliform Macular Dystrophy 2-Like Protein 3 proteinBest3 proteinVmd2l3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
