Anti-ZYX antibody (250-350) [S8MR] (STJ11101808)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Zyxin (250-350) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S8MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZYX |
| Gene ID | 7791 |
| Uniprot ID | ZYX_HUMAN |
| Immunogen Region | 250-350 |
| Immunogen Sequence | TQPRGPPASSPAPAPKFSPV TPKFTPVASKFSPGAPGGSG SQPNQKLGHPEALSAGTGSP QPPSFTYAQQREKPRVQEKQ HPVPPPAQNQNQVRSPGAPG P |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Zyxin (Q15942). |
Additional Info
| Function | Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression. |
| Protein Name | ZyxinZyxin-2 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonNucleusCell JunctionFocal AdhesionAssociates With The Actin Cytoskeleton Near The Adhesion PlaquesEnters The Nucleus In The Presence Of Hesx1 |
| Alternative Antibody Names | Anti-Zyxin antibodyAnti-Zyxin-2 antibodyAnti-ZYX antibody |
Information sourced from Uniprot.org