Anti-ZP3 antibody (210-260 aa) (STJ194009)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ZP3 at the amino acid range 210-260
General Information
| Short Description | Rabbit polyclonal anti-Zona pellucida sperm-binding protein 3 (210-260 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZP3 |
| Gene ID | 7784 |
| Uniprot ID | ZP3_HUMAN |
| Immunogen | Synthesized peptide derived from the human ZP3 at the amino acid range 210-260 |
| Immunogen Region | 210-260 aa |
| Specificity | This antibody detects endogenous levels of ZP3 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. N-glycosylated. O-glycosylated.removal of O-linked glycans may play an important role in the post-fertilization block to polyspermy. |
| Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. |
| Protein Name | Zona Pellucida Sperm-Binding Protein 3Sperm ReceptorZp3a/Zp3bZona Pellucida Glycoprotein 3Zp-3Zona Pellucida Protein C Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 3 |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 3: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Zona Pellucida Sperm-Binding Protein 3 antibodyAnti-Sperm Receptor antibodyAnti-Zp3a/Zp3b antibodyAnti-Zona Pellucida Glycoprotein 3 antibodyAnti-Zp-3 antibodyAnti-Zona Pellucida Protein C Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 3 antibodyAnti-ZP3 antibodyAnti-ZP3A antibodyAnti-ZP3B antibodyAnti-ZPC antibody |
Information sourced from Uniprot.org