Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-NFX1-type zinc finger-containing protein 1 (1657-1707 aa) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ZNFX1 |
Gene ID: | 57169 |
Uniprot ID: | ZNFX1_HUMAN |
Immunogen Region: | 1657-1707 aa |
Specificity: | This antibody detects endogenous levels of ZNFX1 at Human/Mouse |
Immunogen: | Synthesized peptide derived from the human ZNFX1 at the amino acid range 1657-1707 |
Function | RNA-binding protein that initiates the antiviral response and is required to restrict the replication of RNA viruses. Acts as a double-stranded RNA (dsRNA) sensor that recognizes viral RNA and then interacts with MAVS to initiate the type I interferon response. Also required for immunity against some bacteria, such as mycobacteria. |
Protein Name | Nfx1-Type Zinc Finger-Containing Protein 1 |
Cellular Localisation | Mitochondrion Outer MembraneCytoplasmStress Granule |
Alternative Antibody Names | Anti-Nfx1-Type Zinc Finger-Containing Protein 1 antibodyAnti-ZNFX1 antibodyAnti-KIAA1404 antibody |
Information sourced from Uniprot.org