Anti-ZNF768 antibody (140-270) (STJ119807)

Name: Anti-ZNF768 antibody (140-270) (STJ119807)
SKU: STJ119807
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ119807

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Short Description	Rabbit polyclonal ZNF768 (140-270) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ZNF768
Gene ID	79724
Uniprot ID	ZN768_HUMAN
Immunogen Region	140-270
Immunogen Sequence	PGYESESSRYESQNTELKTQ SPEFEAQSSKFQEGAEMLLN PEEKSPLNISVGVHPLDSFT QGFGEQPTGDLPIGPPFEMP TGALLSTPQFEMLQNPLGLT GALRGPGRRGGRARGGQGPR PNICGICGKSF
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 140-270 of human ZNF768 (NP_078947.3).

Post Translational Modifications	May be phosphorylated at residue 'Ser-5' of the tandem heptapeptide repeats in the N-terminus. Phosphorylation might be increased upon RAS pathway activation and negatively regulate protein stability.
Function	Binds to mammalian-wide interspersed repeat (MIRs) sequences in euchromatin and promoter regions of genes at the consensus sequence 5'-GCTGTGTG-N20-CCTCTCTG-3', consisting of two anchor regions connected by a linker region.the linker region probably does not contribute to the binding specificity. Required for cell homeostasis. May be involved in transcriptional regulation (Probable).
Protein Name	Zinc Finger Protein 768
Database Links
Cellular Localisation	Nucleus Chromosome Localizes To Euchromatin
Alternative Antibody Names	Anti-Zinc Finger Protein 768 antibody Anti-ZNF768 antibody

Information sourced from Uniprot.org