| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Zinc finger protein 746 (37-87 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZNF746 |
| Gene ID: | 155061 |
| Uniprot ID: | ZN746_HUMAN |
| Immunogen Region: | 37-87 aa |
| Specificity: | This antibody detects endogenous levels of human ZN746 |
| Immunogen: | Synthesized peptide derived from the human ZN746 at the amino acid range 37-87 |
| Function | Transcription repressor that specifically binds to the 5'-TATTTTT/G-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. |
| Protein Name | Zinc Finger Protein 746Parkin-Interacting SubstrateParis |
| Database Links | Reactome: R-HSA-212436 |
| Cellular Localisation | CytoplasmNucleusMainly Localizes To The CytoplasmProbably Translocates To The Nucleus To Repress Selected Genes |
| Alternative Antibody Names | Anti-Zinc Finger Protein 746 antibodyAnti-Parkin-Interacting Substrate antibodyAnti-Paris antibodyAnti-ZNF746 antibodyAnti-PARIS antibody |
Information sourced from Uniprot.org