| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:100IF/ICC:1:20-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZNF148 |
| Gene ID: | 7707 |
| Uniprot ID: | ZN148_HUMAN |
| Immunogen Region: | 690-794 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 690-794 of human ZNF148 (NP_068799.2). |
| Immunogen Sequence: | SGDETNHASATSTQDFLDQV TSQKKAEAQPVHQAYQMSSF EQPFRAPYHGSRAGIATQFS TANGQVNLRGPGTSAEFSEF PLVNVNDNRAGMTSSPDATT GQTFG |
| Post Translational Modifications | Sumoylated with SUMO2. Desumoylated by SENP3, resulting in the stimulation of transcription of its target genes. |
| Function | Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes. |
| Protein Name | Zinc Finger Protein 148Transcription Factor Zbp-89Zinc Finger Dna-Binding Protein 89 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 148 antibodyAnti-Transcription Factor Zbp-89 antibodyAnti-Zinc Finger Dna-Binding Protein 89 antibodyAnti-ZNF148 antibodyAnti-ZBP89 antibody |
Information sourced from Uniprot.org