Anti-ZNF143 antibody (518-568) (STJA0006353)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ZN143 AA range: 518-568
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger protein 143 (518-568) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZNF143 |
| Gene ID | 7702 |
| Uniprot ID | ZN143_HUMAN |
| Immunogen | Synthesized peptide derived from human ZN143 AA range: 518-568 |
| Immunogen Region | 518-568 |
| Specificity | This antibody detects endogenous levels of human ZN143 |
Additional Info
| Function | Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8. In complex with HCFC1 and ZNF143, regulates the expression of several genes, including AP2S1, ESCO2, OPHN1, RBL1, UBXN8 and ZNF32. |
| Protein Name | Zinc Finger Protein 143Sph-Binding FactorSelenocysteine Trna Gene Transcription-Activating FactorHstaf |
| Database Links | Reactome: R-HSA-6807505Reactome: R-HSA-749476Reactome: R-HSA-76071 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 143 antibodyAnti-Sph-Binding Factor antibodyAnti-Selenocysteine Trna Gene Transcription-Activating Factor antibodyAnti-Hstaf antibodyAnti-ZNF143 antibodyAnti-SBF antibodyAnti-STAF antibody |
Information sourced from Uniprot.org