Anti-ZIC3 antibody (1-240) (STJ111714)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ZIC3 (1-240) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZIC3 |
| Gene ID | 7547 |
| Uniprot ID | ZIC3_HUMAN |
| Immunogen Region | 1-240 |
| Immunogen Sequence | MTMLLDGGPQFPGLGVGSFG APRHHEMPNREPAGMGLNPF GDSTHAAAAAAAAAAFKLSP AAAHDLSSGQSSAFTPQGSG YANALGHHHHHHHHHHHTSQ VPSYGGAASAAFNSTREFLF RQRSSGLSEAASGGGQHGLF AGSASSLHAPAGIPEPPSYL LFPGLHEQGAGHPSPTGHVD NNQVHLGLRGELFGRADPYR PVASPRTDPYAAGAQFPNYS PMNMNMGVNVAAHHGPGAF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ZIC3 (NP_003404.1). |
Additional Info
| Function | Acts as a transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. |
| Protein Name | Zinc Finger Protein Zic 3Zinc Finger Protein 203Zinc Finger Protein Of The Cerebellum 3 |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-452723 |
| Cellular Localisation | NucleusCytoplasmLocalizes In The Cytoplasm In Presence Of Mdfic OverexpressionTranslocation To The Nucleus Requires Kpna1 Or Kpna6 |
| Alternative Antibody Names | Anti-Zinc Finger Protein Zic 3 antibodyAnti-Zinc Finger Protein 203 antibodyAnti-Zinc Finger Protein Of The Cerebellum 3 antibodyAnti-ZIC3 antibodyAnti-ZNF203 antibody |
Information sourced from Uniprot.org