| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ZHX2 (488-837) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZHX2 |
| Gene ID: |
22882 |
| Uniprot ID: |
ZHX2_HUMAN |
| Immunogen Region: |
488-837 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 488-837 of human ZHX2 (NP_055758.1). |
| Immunogen Sequence: |
SDHRYRCQRGIVHITSESLA KDQLAIAASRHGRTYHAYPD FAPQKFKEKTQGQVKILEDS FLKSSFPTQAELDRLRVETK LSRREIDSWFSERRKLRDSM EQAVLDSMGSGKKGQDVGAP NGALSRLDQLSGAQLTSSLP SPSPAIAKSQEQVHLLRSTF ARTQWPTPQEYDQLAAKTGL VRTEIVRWFKENRCLLKTGT VKWMEQYQHQPMADDHGYDA VARKATKPMAESPKNGGDV |
| Tissue Specificity | Ubiquitously expressed. Expressed in podocytes. |
| Function | Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex. |
| Protein Name | Zinc Fingers And Homeoboxes Protein 2Alpha-Fetoprotein Regulator 1Afp Regulator 1Regulator Of AfpZinc Finger And Homeodomain Protein 2 |
| Cellular Localisation | NucleusColocalizes With Efnb1 Intracellular Domain In The Nucleus |
| Alternative Antibody Names | Anti-Zinc Fingers And Homeoboxes Protein 2 antibodyAnti-Alpha-Fetoprotein Regulator 1 antibodyAnti-Afp Regulator 1 antibodyAnti-Regulator Of Afp antibodyAnti-Zinc Finger And Homeodomain Protein 2 antibodyAnti-ZHX2 antibodyAnti-AFR1 antibodyAnti-KIAA0854 antibodyAnti-RAF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
