| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZHX2 |
| Gene ID: | 22882 |
| Uniprot ID: | ZHX2_HUMAN |
| Immunogen Region: | 488-837 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 488-837 of human ZHX2 (NP_055758.1). |
| Immunogen Sequence: | SDHRYRCQRGIVHITSESLA KDQLAIAASRHGRTYHAYPD FAPQKFKEKTQGQVKILEDS FLKSSFPTQAELDRLRVETK LSRREIDSWFSERRKLRDSM EQAVLDSMGSGKKGQDVGAP NGALSRLDQLSGAQLTSSLP SPSPAIAKSQEQVHLLRSTF ARTQWPTPQEYDQLAAKTGL VRTEIVRWFKENRCLLKTGT VKWMEQYQHQPMADDHGYDA VARKATKPMAESPKNGGDV |
| Tissue Specificity | Ubiquitously expressed. Expressed in podocytes. |
| Function | Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex. |
| Protein Name | Zinc Fingers And Homeoboxes Protein 2Alpha-Fetoprotein Regulator 1Afp Regulator 1Regulator Of AfpZinc Finger And Homeodomain Protein 2 |
| Cellular Localisation | NucleusColocalizes With Efnb1 Intracellular Domain In The Nucleus |
| Alternative Antibody Names | Anti-Zinc Fingers And Homeoboxes Protein 2 antibodyAnti-Alpha-Fetoprotein Regulator 1 antibodyAnti-Afp Regulator 1 antibodyAnti-Regulator Of Afp antibodyAnti-Zinc Finger And Homeodomain Protein 2 antibodyAnti-ZHX2 antibodyAnti-AFR1 antibodyAnti-KIAA0854 antibodyAnti-RAF antibody |
Information sourced from Uniprot.org