Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-Zinc Fingers And Homeoboxes Protein 2 (260-500) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S4091RM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ZHX2 |
Gene ID: |
22882 |
Uniprot ID: |
ZHX2_HUMAN |
Immunogen Region: |
260-500 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 260-500 of human ZHX2 (Q9Y6X8). |
Immunogen Sequence: |
VPLNTTKYNSALDTNATMIN SFNKFPYPTQAELSWLTAAS KHPEEHIRIWFATQRLKHGI SWSPEEVEEARKKMFNGTIQ SVPPTITVLPAQLAPTKVTQ PILQTALPCQILGQTSLVLT QVTSGSTTVSCSPITLAVAG VTNHGQKRPLVTPQAAPEPK RPHIAQVPEPPPKVANPPLT PASDRKKTKEQIAHLKASFL QSQFPDDAEVYRLIEVTGLA RSEIKKWFSDHRYRCQRGI |
Tissue Specificity | Ubiquitously expressed. Expressed in podocytes. |
Function | Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex. |
Protein Name | Zinc Fingers And Homeoboxes Protein 2Alpha-Fetoprotein Regulator 1Afp Regulator 1Regulator Of AfpZinc Finger And Homeodomain Protein 2 |
Cellular Localisation | NucleusColocalizes With Efnb1 Intracellular Domain In The Nucleus |
Alternative Antibody Names | Anti-Zinc Fingers And Homeoboxes Protein 2 antibodyAnti-Alpha-Fetoprotein Regulator 1 antibodyAnti-Afp Regulator 1 antibodyAnti-Regulator Of Afp antibodyAnti-Zinc Finger And Homeodomain Protein 2 antibodyAnti-ZHX2 antibodyAnti-AFR1 antibodyAnti-KIAA0854 antibodyAnti-RAF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance