| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase ZFP91 (401-450 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:10000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZFP91 |
| Gene ID: | 80829 |
| Uniprot ID: | ZFP91_HUMAN |
| Immunogen Region: | 401-450 aa |
| Specificity: | The antibody detects endogenous ZFP91 protein |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human ZFP91 at the amino acid range 401-450 |
| Function | Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis. |
| Protein Name | E3 Ubiquitin-Protein Ligase Zfp91Ring-Type E3 Ubiquitin Transferase Zfp91Zinc Finger Protein 757Zinc Finger Protein 91 HomologZfp-91 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Zfp91 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Zfp91 antibodyAnti-Zinc Finger Protein 757 antibodyAnti-Zinc Finger Protein 91 Homolog antibodyAnti-Zfp-91 antibodyAnti-ZFP91 antibodyAnti-ZNF757 antibodyAnti-FKSG11 antibody |
Information sourced from Uniprot.org