Anti-ZDHHC6 antibody (160-210 aa) (STJ195098)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ZDHC6 at the amino acid range 160-210
General Information
| Short Description | Rabbit polyclonal anti-Palmitoyltransferase ZDHHC6 (160-210 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZDHHC6 |
| Gene ID | 64429 |
| Uniprot ID | ZDHC6_HUMAN |
| Immunogen | Synthesized peptide derived from the human ZDHC6 at the amino acid range 160-210 |
| Immunogen Region | 160-210 aa |
| Specificity | This antibody detects endogenous levels of ZDHC6 at Human/Mouse |
Additional Info
| Function | Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC. Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins. Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum. Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Stearoyltransferase that mediates stearoylation of TFRC to inhibit TFRC-mediated activation of the JNK pathway and mitochondrial fragmentation. |
| Protein Name | Palmitoyltransferase Zdhhc6Stearoyltransferase Zdhhc6Transmembrane Protein H4Zinc Finger Dhhc Domain-Containing Protein 6Dhhc-6Zinc Finger Protein 376 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinWhen Not PalmitoylatedAccumulates To Dot-Like Structures In The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc6 antibodyAnti-Stearoyltransferase Zdhhc6 antibodyAnti-Transmembrane Protein H4 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 6 antibodyAnti-Dhhc-6 antibodyAnti-Zinc Finger Protein 376 antibodyAnti-ZDHHC6 antibodyAnti-ZNF376 antibody |
Information sourced from Uniprot.org