| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ZDHHC1 (174-182) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Preliminary experiments gave bands at approx 48kDa and 20kDa in lysates of cell line HEK293 after 2µg/ml antibody staining. Please note that currently we cannot find an explanation in t |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ZDHHC1 |
| Gene ID: | 29800 |
| Uniprot ID: | ZDHC1_HUMAN |
| Immunogen Region: | 174-182 |
| Accession Number: | NP_037436.1 |
| Immunogen Sequence: | RNYRLFLHS |
| Function | Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. Has a palmitoyltransferase activity toward NCDN and regulates NCDN association with endosome membranes through this palmitoylation. Has also a palmitoyltransferase activity-independent function in DNA virus-triggered and CGAS-mediated innate immune response. Functions as an activator of STING1 by promoting its cGAMP-induced oligomerization and the recruitment of downstream signaling components. |
| Protein Name | Palmitoyltransferase Zdhhc1Dhhc Domain-Containing Cysteine-Rich Protein 1Zinc Finger Dhhc Domain-Containing Protein 1Dhhc-1Zinc Finger Protein 377 |
| Cellular Localisation | Endosome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum MembraneGolgi Apparatus |
| Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc1 antibodyAnti-Dhhc Domain-Containing Cysteine-Rich Protein 1 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 1 antibodyAnti-Dhhc-1 antibodyAnti-Zinc Finger Protein 377 antibodyAnti-ZDHHC1 antibodyAnti-C16orf1 antibodyAnti-ZNF377 antibody |
Information sourced from Uniprot.org