Anti-ZBTB16 antibody [5B3] (STJ98325)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of human PLZF expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Zinc finger and BTB domain-containing protein 16 for use in WB, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 5B3 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZBTB16 |
| Gene ID | 7704 |
| Uniprot ID | ZBT16_HUMAN |
| Immunogen | Purified recombinant fragment of human PLZF expressed in E. Coli. |
| Specificity | PLZF Monoclonal Antibody detects endogenous levels of PLZF protein. |
Additional Info
| Function | Acts as a transcriptional repressor. Transcriptional repression may be mediated through recruitment of histone deacetylases to target promoters. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Protein Name | Zinc Finger And Btb Domain-Containing Protein 16Promyelocytic Leukemia Zinc Finger ProteinZinc Finger Protein 145Zinc Finger Protein Plzf |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | NucleusNuclear Body |
| Alternative Antibody Names | Anti-Zinc Finger And Btb Domain-Containing Protein 16 antibodyAnti-Promyelocytic Leukemia Zinc Finger Protein antibodyAnti-Zinc Finger Protein 145 antibodyAnti-Zinc Finger Protein Plzf antibodyAnti-ZBTB16 antibodyAnti-PLZF antibodyAnti-ZNF145 antibody |
Information sourced from Uniprot.org