| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | ZBTB14 |
| Gene ID: | 7541 |
| Uniprot ID: | ZBT14_HUMAN |
| Immunogen Region: | 1-280 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ZBTB14 (NP_003400.2). |
| Immunogen Sequence: | MEFFISMSETIKYNDDDHKT LFLKTLNEQRLEGEFCDIAI VVEDVKFRAHRCVLAACSTY FKKLFKKLEVDSSSVIEIDF LRSDIFEEVLNYMYTAKISV KKEDVNLMMSSGQILGIRFL DKLCSQKRDVSSPDENNGQS KSKYCLKINRPIGDAADTQD DDVEEIGDQDDSPSDDTVEG TPPSQEDGKSPTTTLRVQEA ILKELGSEEVRKVNCYGQEV ESMETPESKDLGSQTPQAL |
| Function | Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters. |
| Protein Name | Zinc Finger And Btb Domain-Containing Protein 14Zinc Finger Protein 161 HomologZfp-161Zinc Finger Protein 478Zinc Finger Protein 5 HomologZf5Zfp-5Hzf5 |
| Cellular Localisation | NucleusColocalizes With Zbtb21 In Nucleus In Hek293 Cells |
| Alternative Antibody Names | Anti-Zinc Finger And Btb Domain-Containing Protein 14 antibodyAnti-Zinc Finger Protein 161 Homolog antibodyAnti-Zfp-161 antibodyAnti-Zinc Finger Protein 478 antibodyAnti-Zinc Finger Protein 5 Homolog antibodyAnti-Zf5 antibodyAnti-Zfp-5 antibodyAnti-Hzf5 antibodyAnti-ZBTB14 antibodyAnti-ZFP161 antibodyAnti-ZNF478 antibody |
Information sourced from Uniprot.org
