| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Xin actin-binding repeat-containing protein 1 (1-51 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | XIRP1 |
| Gene ID: | 165904 |
| Uniprot ID: | XIRP1_HUMAN |
| Immunogen Region: | 1-51 aa |
| Specificity: | This antibody detects endogenous levels of XIRP1 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human XIRP1 at the amino acid range 1-51 |
| Function | Protects actin filaments from depolymerization. Required for correct cardiac intercalated disk ultrastructure via maintenance of cell-cell adhesion stability, and as a result maintains cardiac organ morphology, conductance and heart beat rhythm. Required for development of normal skeletal muscle morphology and muscle fiber type composition. Plays a role in regulating muscle satellite cell activation and survival, as a result promotes muscle fiber recovery from injury and fatigue. |
| Protein Name | Xin Actin-Binding Repeat-Containing Protein 1Cardiomyopathy-Associated Protein 1 |
| Cellular Localisation | Cell JunctionAdherens JunctionDesmosomeColocalizes With Actin Stress Fibers |
| Alternative Antibody Names | Anti-Xin Actin-Binding Repeat-Containing Protein 1 antibodyAnti-Cardiomyopathy-Associated Protein 1 antibodyAnti-XIRP1 antibodyAnti-CMYA1 antibodyAnti-XIN antibody |
Information sourced from Uniprot.org