| Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal embryonic kidney development, and for normal development of the urogenital tract, including uterus and part of the oviduct and the upper vagina in females, and epididymis and vas deferens in males. Activates a signaling cascade in the metanephric mesenchyme that induces tubulogenesis. Acts upstream of WNT4 in the signaling pathways that mediate development of kidney tubules and the Muellerian ducts. Plays a role in cranofacial development and is required for normal fusion of the palate during embryonic development. |
| Protein Name | Protein Wnt-9bProtein Wnt-14bProtein Wnt-15 |
| Database Links | Reactome: R-HSA-3238698Reactome: R-HSA-373080Reactome: R-HSA-9831926 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Protein Wnt-9b antibodyAnti-Protein Wnt-14b antibodyAnti-Protein Wnt-15 antibodyAnti-WNT9B antibodyAnti-WNT14B antibodyAnti-WNT15 antibodyAnti-UNQ6973 antibodyAnti-PRO21956 antibody |
Information sourced from Uniprot.org
