Anti-WNT9A antibody (250-350) (STJ110248)

Name: Anti-WNT9A antibody (250-350) (STJ110248)
SKU: STJ110248
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ110248

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Short Description	Rabbit polyclonal WNT9A (250-350) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	WNT9A
Gene ID	7483
Uniprot ID	WNT9A_HUMAN
Immunogen Region	250-350
Immunogen Sequence	ALKVGSTTNEAAGEAGAISP PRGRASGAGGSDPLPRTPEL VHLDDSPSFCLAGRFSPGTA GRRCHREKNCESICCGRGHN TQSRVVTRPCQCQVRWCCYV E
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human WNT9A (NP_003386.1).

Post Translational Modifications	Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function	Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturation and for normal bone mineralization during embryonic bone development. Plays a redundant role in maintaining joint integrity.
Protein Name	Protein Wnt-9a Protein Wnt-14
Database Links	Reactome: R-HSA-201681 Reactome: R-HSA-3238698 Reactome: R-HSA-373080 Reactome: R-HSA-3772470
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Protein Wnt-9a antibody Anti-Protein Wnt-14 antibody Anti-WNT9A antibody Anti-WNT14 antibody

Information sourced from Uniprot.org