Anti-WNT16 antibody (1-100) [S4100RM] (STJ11104100)

Name: Anti-WNT16 antibody (1-100) [S4100RM] (STJ11104100)
SKU: STJ11104100
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11104100

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Short Description	Rabbit monoclonal Protein Wnt-16 (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S4100RM
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	WNT16
Gene ID	51384
Uniprot ID	WNT16_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MDRAALLGLARLCALWAALL VLFPYGAQGNWMWLGIASFG VPEKLGCANLPLNSRQKELC KRKPYLLPSIREGARLGIQE CGSQFRHERWNCMITAAATT
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Wnt16 (Q9UBV4).

Tissue Specificity	Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas.
Post Translational Modifications	Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function	Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Protein Name	Protein Wnt-16
Database Links	Reactome: R-HSA-3238698 Reactome: R-HSA-373080
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Protein Wnt-16 antibody Anti-WNT16 antibody

Information sourced from Uniprot.org