| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | WNT11 |
| Gene ID: | 7481 |
| Uniprot ID: | WNT11_HUMAN |
| Immunogen Region: | 225-354 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 225-354 of human WNT11 (NP_004617.2). |
| Immunogen Sequence: | KGLQELQDVAADLKTRYLSA TKVVHRPMGTRKHLVPKDLD IRPVKDSELVYLQSSPDFCM KNEKVGSHGTQDRQCNKTSN GSDSCDLMCCGRGYNPYTDR VVERCHCKYHWCCYVTCRRC ERTVERYVCK |
| Tissue Specificity | Expressed in fetal lung, kidney, adult heart, liver, skeletal muscle, and pancreas. |
| Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. |
| Protein Name | Protein Wnt-11 |
| Database Links | Reactome: R-HSA-3238698Reactome: R-HSA-373080Reactome: R-HSA-4086398Reactome: R-HSA-4086400Reactome: R-HSA-9830674 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Protein Wnt-11 antibodyAnti-WNT11 antibody |
Information sourced from Uniprot.org
