Anti-WLS antibody (STJA0007066)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human GPR177
General Information
| Short Description | Rabbit polyclonal anti-Protein wntless homolog for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | WLS |
| Gene ID | 79971 |
| Uniprot ID | WLS_HUMAN |
| Immunogen | Synthesized peptide derived from human GPR177 |
| Specificity | This antibody detects endogenous levels of GPR177 at Human, Mouse, Rat |
Additional Info
| Function | Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. |
| Protein Name | Protein Wntless HomologIntegral Membrane Protein Gpr177Protein Evenness Interrupted HomologEviPutative Nf-Kappa-B-Activating Protein 373 |
| Database Links | Reactome: R-HSA-3238698 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembraneCell MembraneEndoplasmic Reticulum MembraneEarly Endosome MembraneCo-Localizes With The Adaptin Ap2a2 At Distinct Punctae |
| Alternative Antibody Names | Anti-Protein Wntless Homolog antibodyAnti-Integral Membrane Protein Gpr177 antibodyAnti-Protein Evenness Interrupted Homolog antibodyAnti-Evi antibodyAnti-Putative Nf-Kappa-B-Activating Protein 373 antibodyAnti-WLS antibodyAnti-C1orf139 antibodyAnti-GPR177 antibodyAnti-UNQ85 antibodyAnti-PRO18667 antibody |
Information sourced from Uniprot.org