| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-WD repeat-containing protein 62 (984-1034 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | WDR62 |
| Gene ID: | 284403 |
| Uniprot ID: | WDR62_HUMAN |
| Immunogen Region: | 984-1034 aa |
| Specificity: | This antibody detects endogenous levels of WDR62 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human WDR62 at the amino acid range 984-1034 |
| Function | Required for cerebral cortical development. Plays a role in neuronal proliferation and migration. Plays a role in mother-centriole-dependent centriole duplication.the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. |
| Protein Name | Wd Repeat-Containing Protein 62 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindle PoleMicrotubule Organizing CenterCentrosomeCentrioleShows Cell Cycle-Dependent LocalizationAccumulates To The Spindle Pole During MitosisColocalizes With Cdk5rap2Cep152 And Wdr62 In A Discrete Ring Around The Proximal End Of The Parental CentrioleAt This SiteA Cohesive Structure Is Predicted To Engage Parental Centrioles And Procentrioles |
| Alternative Antibody Names | Anti-Wd Repeat-Containing Protein 62 antibodyAnti-WDR62 antibodyAnti-C19orf14 antibody |
Information sourced from Uniprot.org
