| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-WD repeat-containing protein 62 (984-1034 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
WDR62 |
| Gene ID: |
284403 |
| Uniprot ID: |
WDR62_HUMAN |
| Immunogen Region: |
984-1034 aa |
| Specificity: |
This antibody detects endogenous levels of WDR62 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human WDR62 at the amino acid range 984-1034 |
| Function | Required for cerebral cortical development. Plays a role in neuronal proliferation and migration. Plays a role in mother-centriole-dependent centriole duplication.the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. |
| Protein Name | Wd Repeat-Containing Protein 62 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindle PoleMicrotubule Organizing CenterCentrosomeCentrioleShows Cell Cycle-Dependent LocalizationAccumulates To The Spindle Pole During MitosisColocalizes With Cdk5rap2Cep152 And Wdr62 In A Discrete Ring Around The Proximal End Of The Parental CentrioleAt This SiteA Cohesive Structure Is Predicted To Engage Parental Centrioles And Procentrioles |
| Alternative Antibody Names | Anti-Wd Repeat-Containing Protein 62 antibodyAnti-WDR62 antibodyAnti-C19orf14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
