Anti-WASF2 antibody (141-190 aa) (STJ96263)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human WASF2 at the amino acid range 141-190
General Information
| Short Description | Rabbit polyclonal anti-Actin-binding protein WASF2 (141-190 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | WASF2 |
| Gene ID | 10163 |
| Uniprot ID | WASF2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human WASF2 at the amino acid range 141-190 |
| Immunogen Region | 141-190 aa |
| Specificity | WAVE2 Polyclonal Antibody detects endogenous levels of WAVE2 protein. |
Additional Info
| Function | Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. |
| Protein Name | Actin-Binding Protein Wasf2Protein Wave-2Verprolin Homology Domain-Containing Protein 2Wiskott-Aldrich Syndrome Protein Family Member 2Wasp Family Protein Member 2 |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionLamellipodiumBasolateral Cell MembraneAt The Interface Between The Lamellipodial Actin Meshwork And The Membrane |
| Alternative Antibody Names | Anti-Actin-Binding Protein Wasf2 antibodyAnti-Protein Wave-2 antibodyAnti-Verprolin Homology Domain-Containing Protein 2 antibodyAnti-Wiskott-Aldrich Syndrome Protein Family Member 2 antibodyAnti-Wasp Family Protein Member 2 antibodyAnti-WASF2 antibodyAnti-WAVE2 antibody |
Information sourced from Uniprot.org