| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-VWC2L (1-50) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Vwc2l |
| Gene ID: |
320460 |
| Uniprot ID: |
VWC2L_MOUSE |
| Immunogen Region: |
1-50 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-50 of mouse VWC2L (NP_796138.2). |
| Immunogen Sequence: |
MALHIHEACILLLVIPGLVT SAAISHEDYPADEGDQASSN DNLIFDDYRG |
| Tissue Specificity | Predominantly expressed in the brain (at protein level). Also detected in bones, including femur and calvaria, heart, lung and kidney. Isoform 5 is predominant in lung and heart, compared to isoforms 1 and 3. Isoform 4 is expressed in femur and calvaria at higher levels than isoforms 1 and 5. Isoforms 1 and 4 are expressed at higher levels than isoform 5 in kidney and brain. |
| Function | May play a role in neurogenesis. May promote matrix mineralization, but has been shown to weakly, but significantly inhibit BMP2 and BMP6 activity in a preosteoblastic cell line. |
| Protein Name | Von Willebrand Factor C Domain-Containing Protein 2-LikeBrorin-Like |
| Cellular Localisation | SecretedSynapse |
| Alternative Antibody Names | Anti-Von Willebrand Factor C Domain-Containing Protein 2-Like antibodyAnti-Brorin-Like antibodyAnti-Vwc2l antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
